Details of Award

NERC Reference : NER/T/S/2002/00593

Exploring distribution/diversity/pressure adaptation & potential biotechnological significance of prokaryotic ether lipids in non-extreme environments

Principal Investigator:: Professor RJ Parkes, Cardiff University, School of Earth and Ocean Sciences
Co-Investigator:: Professor RD Pancost, University of Bristol, Chemistry
Grant held at:: Cardiff University, School of Earth and Ocean Sciences

Abstract:: Recently, it has been shown that ether membrane lipids, typically associated with archaea and thermophilic bacteria, are considerably more widespread and structurally diverse than previously thought. The goals of this research are to constrain further the structures of these lipids, their biological sources, and the environmental controls on their occurrence. Specifically, we will: 1) further evaluate the occurrence and diversity of ether lipids in non-extreme environments; 2) screen existing MFMB cultures for the presence of ether lipid containing prokaryotes and obtain sufficient biomass for lipid isolation, detailed characterisation and future biotechnological exploitation (e.g. liposomes); 3) use enrichment under pressure to select for organisms with novel ether lipids.

Authorised funds only

This grant award has a total value of £83,317

Total - Staff	Total - T&S	Total - Other Costs	Total - Indirect Costs
£47,490	£1,772	£12,209	£21,845

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