Details of Award
NERC Reference : NER/T/S/2002/00199
Population structure of a segmented RNA animal virus: immune mediated clonality or free reassortment.
Grant Award
- Principal Investigator:
- Dr M Nunn, NERC CEH (Up to 30.11.2019), NERC CEH - Oxford
- Co-Investigator:
- Professor S Wanless, UK Centre for Ecology & Hydrology, UNLISTED
- Co-Investigator:
- Prof. E Gould, Aix-Marseille University, Unit of Emergent Viruses
- Grant held at:
- NERC CEH (Up to 30.11.2019), NERC CEH - Oxford
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Natural Resource Management
- Global Change
- Environmental Risks and Hazards
- Biodiversity
- Science Topics:
- Environmental Genomics
- Population Genetics/Evolution
- Conservation Ecology
- Abstract:
- The aim of this proposal is to understand the mechanisms that maintain pathogen diversity using a genetically and phenotypically polymorphic, globally distributed seabird obligate tick-borne orbivirus that has a segmented double-stranded RNA genome. The organism is particularly well suited to addressing issues of geographical and temporal scale and interaction between virus and host immunity. Permitting a rigorous empirical test of the widely debated theory of immune mediated clonality (Gupta et al., 1994a and 1994b). The molecular evolutionary history of each of the pathogens 10 genes will be investigated and direct estimates of sequence rate parameters obtained. As an additional benefit, the study design will enable an assessment of the impact of virus infection on host mortality and direct estimates of rates and routes of virus transmission in the natural host.
- Period of Award:
- 1 May 2003 - 30 Nov 2006
- Value:
- £262,539 Lead Split Award
Authorised funds only
- NERC Reference:
- NER/T/S/2002/00199
- Grant Stage:
- Completed
- Scheme:
- Directed Pre FEC
- Grant Status:
- Closed
- Programme:
- Environmental Genomics
This grant award has a total value of £262,539
FDAB - Financial Details (Award breakdown by headings)
| Total - Staff | Total - T&S | Total - Other Costs | Total - Indirect Costs |
|---|---|---|---|
| £142,140 | £5,337 | £49,678 | £65,384 |
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