Details of Award
NERC Reference : NER/T/S/2002/00196
RpoN-dependent adaptation in Pseudomonas fluorescens.
Grant Award
- Principal Investigator:
- Professor GM Preston, University of Oxford, Plant Sciences
- Grant held at:
- University of Oxford, Plant Sciences
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Pollution and Waste
- Natural Resource Management
- Global Change
- Environmental Risks and Hazards
- Biodiversity
- Science Topics:
- Environmental Microbiology
- Environmental Genomics
- Abstract:
- The alternative sigma factor standard deviation 54 is predicted to regulate a wide range of traits in Pseudomonas fluorescens SBW25. The full repertoire of genes regulated by standard deviation 54 is unknown. In order to understand the role of standard deviation 54 in P. fluorescens SBW25 it is necessary to identify the components and targets of the standard deviation 54 regulatory network; the effect of environmental factors on standard deviation 54 dependent transcription; and the potential for cross talk between standard deviation 54-activating proteins. Standard deviation 54-activating proteins and standard deviation 54-dependent promoters can be predicted from genome sequence data. These predictions will be used in conjunction with microarray technology and site-directed mutagenesis to generate, test and refine a model of the standard deviation 54 regulatory network. The explanatory power of this model will be tested directly by analysing gene expression and the performance of mutants in the natural environment.
- NERC Reference:
- NER/T/S/2002/00196
- Grant Stage:
- Completed
- Scheme:
- Directed Pre FEC
- Grant Status:
- Closed
- Programme:
- Environmental Genomics
This grant award has a total value of £193,019
FDAB - Financial Details (Award breakdown by headings)
| Total - T&S | Total - Staff | Total - Other Costs | Total - Equipment | Total - Indirect Costs |
|---|---|---|---|---|
| £3,186 | £94,507 | £36,399 | £15,455 | £43,474 |
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