Details of Award
NERC Reference : NER/T/S/2002/00194
The genetic control of phenotypic plasticity in the life-cycle of the free-living nematode Caenorhabditis elegans.
Grant Award
- Principal Investigator:
- Professor ME Viney, University of Bristol, Biological Sciences
- Grant held at:
- University of Bristol, Biological Sciences
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Biodiversity
- Science Topics:
- Environmental Genomics
- Population Genetics/Evolution
- Population Ecology
- Abstract:
- In the life-cycle of C. elegans there is a developmental choice (dauer or non-dauer development), modulated by the worms' environment. This is an example of a phenotypically plastic trait, i.e. an environmentally induced change in phenotype. Isolates of C. elegans vary in their phenotypic plasticity of dauer development. We propose to identify the loci controlling this phenotypic plasticity by a combined analysis of gene expression (using whole genome microarrays) and mapping the quantitative trait loci. We will also investigate fitness consequences of variation in this trait. This work will use the extensive information, methods and genomic resources available with C. elegans to understand the genetic basis and phenotypic consequences of a plastic trait, which is central to understanding GENOTYPE x ENVIRONMENT interactions and how selection acts on them.
- NERC Reference:
- NER/T/S/2002/00194
- Grant Stage:
- Completed
- Scheme:
- Directed Pre FEC
- Grant Status:
- Closed
- Programme:
- Environmental Genomics
This grant award has a total value of £274,099
FDAB - Financial Details (Award breakdown by headings)
| Total - Staff | Total - T&S | Total - Other Costs | Total - Equipment | Total - Indirect Costs |
|---|---|---|---|---|
| £112,297 | £4,303 | £73,947 | £20,365 | £63,187 |
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