Details of Award
NERC Reference : NER/T/S/2002/00189
QTL mapping in natural populations using linkage and linkage disequilibrium.
Grant Award
- Principal Investigator:
- Professor JM Pemberton, University of Edinburgh, Inst of Evolutionary Biology
- Co-Investigator:
- Professor J Slate, University of Sheffield, School of Biosciences
- Co-Investigator:
- Professor P Visscher, University of Queensland, Queensland Brain Institute
- Grant held at:
- University of Edinburgh, Inst of Evolutionary Biology
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Biodiversity
- Science Topics:
- Environmental Genomics
- Abstract:
- We will investigate the genetic architecture underlying quantitative variation an selected morphometric and life history traits in a free-living population, the Soay sheep on St. Kilda. (1) We will conduct a full-genome scan for QTL using microsatellite markers and linkage mapping within a series of large, connected, sibships. (2) We will generate SNP markers in targeted regions around already-known candidate QTL, to investigate the relationship between linkage disequilibrium (LD) and genetic distance in order to determine the feasibility of LD mapping in the study population. (3) If LD mapping is feasible, we will fine-map other candidate QTL emerging from our own linkage mapping and from studies of domestic sheep.
- NERC Reference:
- NER/T/S/2002/00189
- Grant Stage:
- Completed
- Scheme:
- Directed Pre FEC
- Grant Status:
- Closed
- Programme:
- Environmental Genomics
This grant award has a total value of £457,579
FDAB - Financial Details (Award breakdown by headings)
| Total - T&S | Total - Staff | Total - Other Costs | Total - Equipment | Total - Indirect Costs |
|---|---|---|---|---|
| £5,118 | £178,996 | £163,251 | £27,877 | £82,338 |
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