Details of Award
NERC Reference : NER/T/S/2002/00181
Comparative genome architecture of the hominids - biological, evolutionary and ecological significance.
Grant Award
- Principal Investigator:
- Dr P Dear, Medical Research Council (MRC), Molecular Biology Laboratory
- Grant held at:
- Medical Research Council (MRC), Molecular Biology Laboratory
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Biodiversity
- Science Topics:
- Environmental Genomics
- Systematics & Taxonomy
- Population Genetics/Evolution
- Conservation Ecology
- Abstract:
- The aim of this project is a detailed comparison of the genomes of all of the hominid species - chimpanzee, bonobo, gorilla, orangutan and man. The project has been designed to reveal the changes in genome architecture and organisation that are believed to play a key role in speciation. We will use a uniquely appropriate technique to construct, for the first time, genome maps of all the species at progressively higher resolution, revealing both the general nature and specific instances of chromosomal rearrangements. We will also survey the genomes for duplications, and correlate these with differential gene expression. Our findings will both complement and support genome sequencing projects, and are of direct relevance to basic biology, to biodiversity and conservation, biomedicine, and to the mechanisms of evolution and speciation.
- NERC Reference:
- NER/T/S/2002/00181
- Grant Stage:
- Completed
- Scheme:
- Directed Pre FEC
- Grant Status:
- Closed
- Programme:
- Environmental Genomics
This grant award has a total value of £203,061
FDAB - Financial Details (Award breakdown by headings)
| Total - Staff | Total - T&S | Total - Other Costs | Total - Indirect Costs | Total - Equipment |
|---|---|---|---|---|
| £101,403 | £2,093 | £33,395 | £46,645 | £19,525 |
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