Details of Award
NERC Reference : NER/T/S/2001/00282
Environmental fitness of Burkholderia cepacia complex: feasibility of testing with the genomic approach of signature-tagged transponson mutagenesis
Grant Award
- Principal Investigator:
- Professor RJ Balment, The University of Manchester, Life Sciences
- Co-Investigator:
- Dr G Cramb, University of St Andrews, Sch of Medicine
- Co-Investigator:
- Dr N Hazon, University of St Andrews, Biology
- Grant held at:
- The University of Manchester, Life Sciences
- Science Area:
- Marine
- Freshwater
- Overall Classification:
- Freshwater
- ENRIs:
- Natural Resource Management
- Global Change
- Biodiversity
- Science Topics:
- Environmental Physiology
- Environmental Genomics
- Abstract:
- The ability of some fish to survive in both freshwater and seawater represents one of the most extreme examples of adaptive physiology in the animal kingdom. This project will identify novel genes which are differentially expressed in response to hypo- and hyper-osmotic challenge in teleost fish. This will be achieved by the screening of micro arrays constructed for two native euryhaline species, the eel and flounder. In a second phase the project will examine in detail a selected number of novel differentially expressed genes using molecular, biochemical and physiological techniques to define the function of these systems in relation to osmotic changes in the environment. The results will provide a more complete picture of the mechanisms and pathways involved in the control of osmoregulation in teleost fish to be constructed.
- NERC Reference:
- NER/T/S/2001/00282
- Grant Stage:
- Completed
- Scheme:
- Directed Pre FEC
- Grant Status:
- Closed
- Programme:
- Environmental Genomics
This grant award has a total value of £979,422
FDAB - Financial Details (Award breakdown by headings)
| Total - T&S | Total - Staff | Total - Other Costs | Total - Indirect Costs | Total - Equipment |
|---|---|---|---|---|
| £21,491 | £398,732 | £289,544 | £205,310 | £64,348 |
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