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Details of Award

NERC Reference : NER/M/S/2001/00113

Contaminant-induced suppression of innate immunity in seals.

Grant Award

Principal Investigator:
Dr EA Dyrynda, Swansea University, Biological Sciences
Science Area:
Marine
Overall Classification:
Marine
ENRIs:
Environmental Risks and Hazards
Science Topics:
Environmental Physiology
Abstract:
The project hypothesis is that two closely related seal species, the harbour seal and the grey seal, exhibit critical differences in innate immunity that are exacerbated with contaminant exposure. These species form sympatric populations in the UK and observations during epizootics indicated very differing disease susceptibilities. The innate immune system is crucial in successful defence against infection and yet almost no details are known about this aspect of immunity in marine mammals. The proposed research will comprise (i) assessment and comparison of innate immune parameters in the 2 named species (ii) in vitro immune assays to test whether exposure to contaminants significantly alters immune activity and (iii) the provision of baseline data on contaminant-immune interactions in seals and its interpretation in the light of long-term field studies.
Period of Award:
8 Feb 2002 - 7 Oct 2002
Value:
£48,547 Lead Split Award
Authorised funds only
NERC Reference:
NER/M/S/2001/00113
Grant Stage:
Completed
Scheme:
New Investigators Pre FEC
Grant Status:
Closed

This grant award has a total value of £48,547  

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FDAB - Financial Details (Award breakdown by headings)

Total - T&STotal - StaffTotal - Other CostsTotal - Indirect Costs
£4,593£21,890£11,995£10,070

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