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Details of Award

NERC Reference : NER/F/S/2001/00272

Genome analysis in molecular, evolutionary and microbial ecology.

Grant Award

Principal Investigator:
Professor G Carvalho, University of Hull, Biological Sciences
Co-Investigator:
Professor GF Turner, Bangor University, Sch of Natural Sciences
Co-Investigator:
Professor TA Paget, University of Sunderland, Sch of Pharmacy & Pharmaceutical Sci
Co-Investigator:
Dr DH Lunt, University of Hull, Biology
Science Area:
Terrestrial
Marine
Freshwater
Overall Classification:
Freshwater
ENRIs:
Pollution and Waste
Natural Resource Management
Biodiversity
Science Topics:
Pollution
Population Genetics/Evolution
Conservation Ecology
Technol. for Environ. Appl.
Abstract:
Eleven academic staff, 15 PDRAs and 23 postgraduates in the Faculty of Science at Hull are engaged in aspects of genome analyses requiring automated DNA analysis facilities. The program (currently #2.5m external funding) includes studies on population analysis and evolution of adaptive variation, speciation in aquatic taxa, the molecular ecology of ancient/recovered DNA, environmental genomics, fisheries genetics and microbial molecular ecology. These activities depend on 2 ALFexpress sequencers which are over-used, relatively labour-intensive, and have very modest output. Recent expansion in demand following increased interdisciplinary (Depts Chemistry, Medicine and Geography) and external collaborations, and new staff appointments, now limits capacity and scope for new initiatives. Here we seek support for a MegaBACE 500 Capillary DNA sequencer, a WAVE DNA analysis system and RoboSeq PCR Robot and plate reader. This equipment will increase capacity, efficiency and exploit new approaches of genomic analysis through establishing a fully integrated high throughput DNA analysis facility. External contributions of #57K (NHS, Scottish Parasite Diagnostics, Manufacturer's discounts) and University support of #188K, including provision of a dedicated University-funded Laboratory Manager, represent good value for money, as well as endorsing University investment in genomic and cellular technologies in environmental sciences at Hull.
Period of Award:
30 Sep 2002 - 29 Sep 2007
Value:
£128,000
Authorised funds only
NERC Reference:
NER/F/S/2001/00272
Grant Stage:
Completed
Scheme:
JREI Pre FEC
Grant Status:
Closed
Programme:
JREI

This grant award has a total value of £128,000  

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FDAB - Financial Details (Award breakdown by headings)

Total - Equipment
£128,000

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