Details of Award
NERC Reference : NER/B/S/2001/00381
Inbreeding and sperm abnormalities in the European rabbit.
Grant Award
- Principal Investigator:
- Professor MJ Gage, University of East Anglia, Biological Sciences
- Co-Investigator:
- Dr D Bell, University of East Anglia, Biological Sciences
- Co-Investigator:
- Professor GM Hewitt, University of East Anglia, Biological Sciences
- Grant held at:
- University of East Anglia, Biological Sciences
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Natural Resource Management
- Environmental Risks and Hazards
- Biodiversity
- Science Topics:
- Population Genetics/Evolution
- Population Ecology
- Conservation Ecology
- Behavioural Ecology
- Abstract:
- Sperm abnormality is a widespread but poorly-understood phenomenon. Elevated proportions of abnormal sperm are associated with compromised fertility in animals and humans, and endangered mammals with abnormal sperm may suffer direct reproductive costs. Sperm abnormalities may result from depleted heterozygosity through inbreeding. This project will examine whether inbreeding generates increased abnormalities in natural and laboratory populations of the European rabbit Oryctolagus cuniculus. We will recover and analyse sperm (and other reproductive traits) from natural and domestic populations that vary widely in heterozygosity. Genetic screening using established polymorphic microsatellite loci will enable a direct test of the effects of natural and experimental inbreeding on the production of abnormal sperm in a mammalian model.
- NERC Reference:
- NER/B/S/2001/00381
- Grant Stage:
- Completed
- Scheme:
- Small Grants Pre FEC
- Grant Status:
- Closed
- Programme:
- Small Grants
This grant award has a total value of £31,289
FDAB - Financial Details (Award breakdown by headings)
| Total - T&S | Total - Staff | Total - Other Costs | Total - Indirect Costs |
|---|---|---|---|
| £1,845 | £16,399 | £5,502 | £7,544 |
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