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Natural Environment Research Council
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Details of Award

NERC Reference : NE/V001566/1

Identifying the genetic targets of sexual selection

Grant Award

Principal Investigator:
Professor M Ritchie, University of St Andrews, Biology
Science Area:
Terrestrial
Overall Classification:
Panel C
ENRIs:
Biodiversity
Science Topics:
Evolutionary biology
Sexual selection
Behavioural Ecology
Evolution & populations
Evolutionary genetics
Gene targeting
Molecular evolution
Speciation
Evolution & populations
Abstract:
Sexual selection influences genomic divergence, for example genes which show sex-biased gene expression are often the most divergent between species. This is sometimes more pronounced in sexually dimorphic species and is therefore thought to reflect the strength of sexual selection. Currently different (even contrasting) patterns of genomic divergence can be interpreted as supporting an influence of sexual selection and conflict on genomic divergence. The resolution and reliability of such patterns is highly debated and unclear. Identifying the precise targets of sexual selection and the signature this leaves in the genome is critical to understanding the importance of this form of selection in evolutionary divergence and speciation. The proposed work will provide an exceptional contribution to resolving how sexual selection acts on genotypes, by leveraging an experimental evolution study which has identified several candidate genes. We will complete functional genetic analyses to confirm the role of these genes and measure the fitness consequences of gene knock outs. We will then upscale this to natural populations and assess the performance of genomic signatures of divergence in natural populations from a range of ecological contexts and levels of evolutionary divergence. This work will provide unprecedented insight into the role of sexual selection in genomic divergence.
Period of Award:
1 Nov 2020 - 31 Dec 2024
Value:
£497,744
Authorised funds only
NERC Reference:
NE/V001566/1
Grant Stage:
Awaiting Event/Action
Scheme:
Standard Grant FEC
Grant Status:
Active
Programme:
Standard Grant

This grant award has a total value of £497,744  

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FDAB - Financial Details (Award breakdown by headings)

DI - Other CostsIndirect - Indirect CostsDA - InvestigatorsDI - StaffDA - Estate CostsDI - T&SDA - Other Directly Allocated
£96,950£135,315£27,359£131,610£40,707£15,854£49,947

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