Details of Award
NERC Reference : NE/G006938/2
Testing the role of spatial structure in ecology and evolution
Grant Award
- Principal Investigator:
- Professor M Boots, University of Exeter, Biosciences
- Co-Investigator:
- Professor S Rolfe, University of Sheffield, School of Biosciences
- Co-Investigator:
- Professor D Childs, University of Sheffield, School of Biosciences
- Grant held at:
- University of Exeter, Biosciences
- Science Area:
- None
- Overall Classification:
- Terrestrial
- ENRIs:
- None
- Science Topics:
- None
- Abstract:
- Individuals tend to interact more with individuals that are close to them or in their social group. Similarly in diseases that are spread by contact, infected individuals are more likely to contact other individuals that are close by or in their social group. The disease therefore spreads spatially through the population. There has been a number of computer models that show that this spatial spread can have a major effect on the disease dynamics. Recent work has shown that this spatial structure can also have important implications to the evolution of parasites. If they spread locally, they are selected for lower transmission and virulence. It is very difficult to test this sort of theory, but we have developed an insect virus system in which we can manipulate how locally the hosts move. Our recent work using this system has confirmed the predictions of the model of the effect of space on transmission; it was lower in a more viscose population. We now want to examine the role of spatial structure on the coevolution of the host in addition to the parasite. As such we propose to build computer models and use some mathematical approximation techniques to predict the effect of local infection on host resistance. We will then test this using our insect virus system. This mixture of theory and ecological experimentation will give us a much clearer idea of the implications of different degrees of local interactions on the evolution of disease causing organisms. Given that anthropological changes are altering the mixing patterns within many populations, it is important that we understand what the implications are to wildlife and human disease.
- NERC Reference:
- NE/G006938/2
- Grant Stage:
- Completed
- Scheme:
- Standard Grant (FEC)
- Grant Status:
- Closed
- Programme:
- Standard Grant
This grant award has a total value of £207,804
FDAB - Financial Details (Award breakdown by headings)
| DI - Other Costs | Indirect - Indirect Costs | DA - Investigators | DI - Equipment | DI - Staff | DA - Estate Costs | DI - T&S | DA - Other Directly Allocated |
|---|---|---|---|---|---|---|---|
| £7,715 | £51,887 | £13,875 | £8,411 | £104,327 | £13,907 | £6,547 | £1,136 |
If you need further help, please read the user guide.