Details of Award
NERC Reference : NE/F012578/1
Molecular and ecological investigations into the infection process of Eurychasma dicksonii on brown algae
Grant Award
- Principal Investigator:
- Professor P Van West, University of Aberdeen, School of Medical Sciences
- Grant held at:
- University of Aberdeen, School of Medical Sciences
- Science Area:
- Marine
- Overall Classification:
- Marine
- ENRIs:
- Biodiversity
- Science Topics:
- Environmental Microbiology
- Environmental Genomics
- Abstract:
- Many of the most devastating agricultural and aquacultural pathogens belong to the group of oomycetes. In addition, many oomycetes seriously impact upon the ecology of natural populations. In coastal marine ecosystems, the oomycete Eurychasma dicksonii is thought to contribute to shaping populations of brown algae. It not only has the largest reported host range among marine pathogens - infecting virtually every brown algal species tested so far, but it is also the most prevalent eukaryotic pathogen in natural brown macroalgal populations. Remarkably, virtually nothing is known about many fundamental aspects of pathogenicity, biology, epidemiology, and ecology of E. dicksonii. As part of the Oceans 2025 core strategic program, we are currently developing tools to study the impact of E. dicksonii epidemics on algal populations and coastal ecosystems. However, many unresolved biological questions are of critical importance to underpin this undertaking. Understanding why E. dicksonii has such a wide host-range, what makes this pathogen so successful, and what pathogenicity determinants and infection strategies it uses to infect its hosts will shed light on how natural brown algal populations are affected by epidemic outbreaks of E. dicksonii, and how this pathogen might influence their genetic structure. This application aims to address these issues in more detail. Identified determinants of host specificity will further be correlated to the genetic and biogeographical background of the pathogen from sites around the world. At the completion of this study, we expect to demonstrate that E. dicksonii is secreting effector molecules that may be translocated into the host cells, and that are under diversifying selection. We hope to generate precise hypotheses on their role in the biotrophic interaction of E. dicksonii with its hosts, as well as its impact on natural brown algal populations.
- Period of Award:
- 1 Aug 2008 - 31 Jan 2012
- Value:
- £243,144 Lead Split Award
Authorised funds only
- NERC Reference:
- NE/F012578/1
- Grant Stage:
- Completed
- Scheme:
- Directed (Research Programmes)
- Grant Status:
- Closed
- Programme:
- SOFI
This grant award has a total value of £243,144
FDAB - Financial Details (Award breakdown by headings)
| DI - Other Costs | Indirect - Indirect Costs | DA - Investigators | DI - Equipment | DA - Estate Costs | DI - Staff | DI - T&S | DA - Other Directly Allocated |
|---|---|---|---|---|---|---|---|
| £42,229 | £78,178 | £20,149 | £2,800 | £17,516 | £77,108 | £2,533 | £2,630 |
If you need further help, please read the user guide.