Details of Award
NERC Reference : NE/F001371/1
Sequencing and the molecular dissection of a 'fitness' locus in Soay sheep
Grant Award
- Principal Investigator:
- Professor J Slate, University of Sheffield, Animal and Plant Sciences
- Co-Investigator:
- Professor JM Pemberton, University of Edinburgh, Sch of Biological Sciences
- Grant held at:
- University of Sheffield, Animal and Plant Sciences
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Global Change
- Biodiversity
- Science Topics:
- Environmental Genomics
- Population Genetics/Evolution
- Abstract:
- This proposal will exploit recent discoveries made under NERC EG project 'QTL mapping in natural populations using linkage and linkage disequilibrium' to address a major question in evolutionary genetics: are negative genetic correlations due to pleiotropy at a single locus, or linkage disequilibrium between closely linked loci? We have identified a negative genetic correlation for fitness in the vicinity of the TYRP1 gene underlying a coat colour polymorphism in Soay sheep. We propose to characterise sequence diversity and patterns of linkage disequilibrium in an ~600 Kbp region flanking TYRP1 in order to dissect the molecular basis of the genetic correlation.
- NERC Reference:
- NE/F001371/1
- Grant Stage:
- Completed
- Scheme:
- Directed (Research Programmes)
- Grant Status:
- Closed
- Programme:
- Post Genomics & Proteomics
This grant award has a total value of £22,984
FDAB - Financial Details (Award breakdown by headings)
| DI - Other Costs | Indirect - Indirect Costs | DA - Investigators | DI - Staff | DA - Estate Costs | DA - Other Directly Allocated |
|---|---|---|---|---|---|
| £8,866 | £6,208 | £1,684 | £4,332 | £1,768 | £125 |
If you need further help, please read the user guide.