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Details of Award

NERC Reference : NE/C507710/1

Identifying & defining bases of individual & population susceptibility & adaptation to environmental pollutants in fish: An integrated 'omic' approach

Grant Award

Principal Investigator:
Professor JK Chipman, Glasgow Caledonian University, Sch of Health and Life Sciences
Co-Investigator:
Dr M Waldock, CEFAS, CEFAS - Weymouth Lab
Co-Investigator:
Professor M Viant, University of Birmingham, Sch of Biosciences
Co-Investigator:
Professor CR Tyler, University of Exeter, Biosciences
Co-Investigator:
Dr S Minchin, University of Birmingham, Sch of Biosciences
Co-Investigator:
Professor sg george, University of Stirling, Institute of Aquaculture
Co-Investigator:
Professor C Moffat, Robert Gordon's College, Grants Administration
Co-Investigator:
Dr JB Taggart, University of Stirling, Institute of Aquaculture
Co-Investigator:
Professor F Falciani, University of Liverpool, Institute of Integrative Biology
Co-Investigator:
Professor J Craft, Glasgow Caledonian University, Sch of Health and Life Sciences
Co-Investigator:
Dr M Leaver, University of Stirling, Institute of Aquaculture
Science Area:
Marine
Freshwater
Overall Classification:
Freshwater
ENRIs:
Pollution and Waste
Natural Resource Management
Environmental Risks and Hazards
Biodiversity
Science Topics:
Ecotoxicology
Environmental Genomics
Population Genetics/Evolution
Environmental Informatics
Abstract:
The identification and assessment of organismal and ecosystem responses to, adaptation to, and selection by multiple pollutants is a major challenge. This interdisciplinary consortium will utilise functional toxicogenomics and metabolomics based upon techniques which place no a priori emphasis on the currently limited knowledge of genotypic and phenotypic responses in marine and freshwater fish (flounder and stickleback) to toxic anthropogenic inputs. The aim of the programme is to inform on 'what makes fish populations resistant or vulnerable to environmental change and impact'. We wish to identify the key genetic and phenotypic determinants for the resistance and vulnerability of these species and their populations to anthropogenic pollutant impact. Furthermore the proposed approach addresses another important basic question, 'does chronic pollution of UK estuaries and rivers reduce the genetic diversity of their fish populations'. It will also have another important practical 'spin off' for end users in that it will enable development of a more appropriate methodology and set of practical tools (including in vitro cell culture systems and biomarkers) to contribute to environmental impact assessment and regulation of discharges by the regulatory authorities. This will provide a more informed knowledge of the health of the aquatic environment thus protecting our aquatic resources and biodiversity.
Period of Award:
1 Oct 2004 - 30 Sep 2008
Value:
£259,066 Split Award
Authorised funds only
NERC Reference:
NE/C507710/1
Grant Stage:
Completed
Scheme:
Directed Pre FEC
Grant Status:
Closed
Programme:
Post Genomics

This grant award has a total value of £259,066  

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FDAB - Financial Details (Award breakdown by headings)

Total - T&STotal - StaffTotal - Other CostsTotal - Indirect CostsTotal - Equipment
£1,247£111,477£51,061£51,279£44,000

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