Details of Award

NERC Reference : NE/C507202/1

Gastrointestinal parasites, the MHC and parasite-mediated selection in a wild avian population.

Principal Investigator:: Professor Ds Richardson, University of East Anglia, Biological Sciences
Grant held at:: University of East Anglia, Biological Sciences

ENRIs:: Biodiversity
Science Topics:: Population Genetics/Evolution; Population Ecology; Conservation Ecology; Behavioural Ecology

Abstract:: Gastrointestinal (GI) parasites, e.g. tapeworms, occur worldwide and can be extremely detrimental to the fitness of individuals. Within vertebrates, the variety of major histocompatibility complex (MHC) genes within an individual determines how well it copes with the diverse array of parasites it encounters in its environment. An individuals' fitness (survival and reproductive success) will therefore, at least in part, depend upon the MHC genes it contains. Few studies have assessed the impact of GI parasites from an evolutionary perspective, and even fewer have taken into account the affect of the MHC. None have done so using birds. We propose to develop a non-invasive protocol, based on modern molecular PCR methods, to determine the type and intensity of GI parasites infections in individual Seychelles warblers (Acrocephalus sechellensis). We will use this protocol, in conjunction with an MHC screening method, to investigate the affect of GI parasites and their interaction with the MHC in the simple and isolated system provided by the Seychelles warbler. This system contains limited genetic variation and few parasites. Thus making easier to study and understand than is often the case in other systems, where the overwhelming complexity of MHC diversity and host-parasite interactions makes investigations extremely difficult.

Authorised funds only

This grant award has a total value of £52,658

Total - Staff	Total - T&S	Total - Other Costs	Total - Indirect Costs
£27,176	£3,439	£9,542	£12,501

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