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Details of Award

NERC Reference : NE/B504249/2

Using Y chromosome haplotype diversity to test for selection within and between natural populations of the plant Silene latifolia.

Grant Award

Principal Investigator:
Professor D Charlesworth, University of Oxford, Plant Sciences
Co-Investigator:
Professor D Filatov, University of Oxford, Biology
Science Area:
Terrestrial
Overall Classification:
Terrestrial
ENRIs:
Biodiversity
Science Topics:
Population Genetics/Evolution
Abstract:
This proposal is to combine data on sequence differences of various kinds, with different mutational time-scales, and information on the geographical distributions of variants, in order to test whether selection is affecting the frequencies of different Y-chromosomes in Silene latifolia and S. dioica. We propose to do this by isolating new Y-linked genes, and resequencing them in plants from multiple wild European populations, so as to define haplotypes based on low mutation rate variants, and to study the ages of the haplotypes in finer detail using higher mutation rate variants (microsatellites). This can indicate whether certain Y chromosome genotypes are locally adapted, or are advantageous across different populations. As well as providing interesting data on the effects of selection on Y chromosomes, the results will allow us to test whether selection causing local adaptation can explain the puzzling observation that Y chromosome variants in these species tend to be at intermediate frequencies, and whether such adaptation contributes to lower diversity of Y-linked variants, compared with variants in the X-linked homologues.
Period of Award:
1 Sep 2007 - 31 Dec 2007
Value:
£12,813 Split Award
Authorised funds only
NERC Reference:
NE/B504249/2
Grant Stage:
Completed
Scheme:
Standard Grants Pre FEC
Grant Status:
Closed
Programme:
Standard Grant

This grant award has a total value of £12,813  

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FDAB - Financial Details (Award breakdown by headings)

Total - StaffTotal - T&STotal - Other CostsTotal - Indirect Costs
£7,743£267£1,241£3,562

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