Details of Award
NERC Reference : NER/A/S/2001/00622
Use of molecular markers to detect selection in nature.
Grant Award
- Principal Investigator:
- Professor L Partridge, University College London, Genetics Evolution and Environment
- Co-Investigator:
- Professor D Goldstein, University College London, Biology at Galton Laboratory
- Grant held at:
- University College London, Genetics Evolution and Environment
- Science Area:
- Terrestrial
- Overall Classification:
- Terrestrial
- ENRIs:
- Natural Resource Management
- Global Change
- Biodiversity
- Science Topics:
- Environmental Genomics
- Population Genetics/Evolution
- Climate & Climate Change
- Abstract:
- In principle, linkage disequilibrium or associations between alleles at polymorphic loci can be used to map Quantitative Trait Loci (QTL), dispensing with the need for traditional QTL mapping. The aim of this project is to test the principle of using molecular markers to detect QTL of clinally selected traits. To do this we will construct a fine-scale QTL map of body size variation in Drosophila melanogaster using naturally diverged lines, and then examine associations between locations of identified QTL and molecular markers in populations along a latitudinal cline. These data will also provide important information on the gene target(s) of thermal selection, and therefore open the way to an understanding of the mechanisms underlying the pervasive, but still mysterious effects of temperature on body size in ectotherms.
- NERC Reference:
- NER/A/S/2001/00622
- Grant Stage:
- Completed
- Scheme:
- Standard Grants Pre FEC
- Grant Status:
- Closed
- Programme:
- Standard Grant
This grant award has a total value of £79,049
FDAB - Financial Details (Award breakdown by headings)
| Total - Staff | Total - T&S | Total - Other Costs | Total - Indirect Costs |
|---|---|---|---|
| £30,824 | £938 | £33,109 | £14,179 |
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